Anhui Zhifei Longcom COVID-19 vaccine: Zifivax (Authorized) [1] |
Not recommended yet |
Not recommended yet |
Not recommended yet |
INVIMA/Colombia: Three doses (0.5 mL each) 4 and 8 weeks apart. |
INVIMA/Colombia: contraindicated in pregnant women. |
Not recommended yet |
Not recommended yet |
Not recommended yet |
INVIMA/Colombia: primary series of three doses (0.5 mL each) 4 and 8 weeks apart. |
There is no available data on interchangeability. |
There is no available data on booster doses beyond the third dose. |
AstraZeneca/Oxford; AstraZeneca/SK BIO; Serum Institute of India COVID-19 vaccine: Vaxzevria; Covishield (EUL/WHO authorization) [2] |
Not recommended yet |
Not recommended yet |
Not recommended yet |
SAGE/WHO: Two doses (0.5 mL each) 4 to 12 weeks apart. WHO recommends an interval of 8 to 12 weeks between doses. |
SAGE/WHO: Two doses (0.5 mL each) 8 to 12 weeks apart. WHO recommends using the Vaxzevria/Covishield COVID-19 vaccine in pregnant women only if the benefits of vaccination outweigh the potential risks. |
Not recommended yet |
Not recommended yet |
Not recommended yet |
SAGE/WHO: Extended primary series with an additional (third) dose of 0.5 mL 1-3 months after the second dose, followed by a booster (fourth) dose provided 3-6 months after. |
SAGE/WHO: Vaxzevria/Covishield combined with any other EUL COVID-19 vaccine is considered a complete primary series. |
SAGE/WHO: A booster dose should be given 4-6 months after the primary series* using any other EUL vaccine (preferably an mRNA-based or Novavax vaccine). |
Bharat Biotech COVID-19 vaccine: Covaxin (EUL/WHO authorization, suspended supply) [3] |
Not recommended yet |
Not recommended yet |
Not recommended yet |
SAGE/WHO: Two doses (0.5 mL each) 4 weeks apart. |
SAGE/WHO: Two doses (0.5 mL each) 4 weeks apart. WHO recommends using the Bharat Biotech COVID-19 vaccine in pregnant women only if the benefits of vaccination outweigh the potential risks. |
Not recommended yet |
Not recommended yet |
Not recommended yet |
SAGE/WHO: Extended primary series with an additional (third) dose of 0.5 mL 1-3 months after the second dose, followed by a booster (fourth) dose provided 3-6 months after. |
SAGE/WHO: Bharat Biotech COVID-19 vaccine combined with any other EUL COVID-19 vaccine is considered a complete primary series. |
SAGE/WHO: A booster dose should be given 4-6 months after the primary series*. |
CanSino COVID-19 vaccine: Convidecia (EUL/WHO authorization) [4] |
Not recommended yet |
Not recommended yet |
Not recommended yet |
SAGE/WHO: One dose of 0.5 mL. |
SAGE/WHO: One dose of 0.5 mL. WHO recommends using the CanSino COVID-19 vaccine in pregnant women only if the benefits of vaccination outweigh the potential risks. |
Not recommended yet |
Not recommended yet |
Not recommended yet |
SAGE/WHO: Extended primary series with an additional (second) dose administered 1-3 months after the first dose. |
SAGE/WHO: CanSino COVID-19 vaccine may be used as a booster dose following a primary series using any other EUL COVID-19 vaccine. |
SAGE/WHO: A booster dose should be given 4-6 months after the primary series*. |
CIGB COVID-19 vaccine: Abdala (Authorized) [5] |
CECMED/Cuba: 2 years of age and older. Three doses (0.5 mL) 2 weeks apart. |
CECMED/Cuba: Three doses (0.5 mL) 2 weeks apart. |
CECMED/Cuba: Three doses (0.5 mL) 2 weeks apart. |
CECMED/Cuba: Three doses (50 µg, 0.5 mL) 2 weeks apart. |
CECMED/Cuba: if the benefits of the vaccination outweigh the potential risks. |
CECMED/Cuba: 2 years of age and older. Three doses (0.5 mL) 2 weeks apart. |
CECMED/Cuba: Three doses (0.5 mL) 2 weeks apart. |
CECMED/Cuba: Three doses (0.5 mL) 2 weeks apart. |
CECMED/Cuba: Three doses (50 µg, 0.5 mL) 2 weeks apart. |
There is no available data on interchangeability. |
There is no available data on booster doses. |
Finlay Institute of Vaccines COVID-19 vaccine: Soberana 02; Soberana Plus (Authorized) [6] |
CECMED/Cuba: SOBERANA 02 and SOBERANA 02 ST: 2 years of age and older. Two doses (0.5 mL) 4 weeks apart. SOBERANA PLUS and SOBERANA PLUS as a booster dose 4 weeks after. |
CECMED/Cuba: SOBERANA 02 and SOBERANA 02 ST: Two doses (0.5 mL) 4 weeks apart. SOBERANA PLUS and SOBERANA PLUS as a booster dose 4 weeks after. |
CECMED/Cuba: SOBERANA 02 and SOBERANA 02 ST: Two doses (0.5 mL) 4 weeks apart. SOBERANA PLUS and SOBERANA PLUS as a booster dose 4 weeks after. |
CECMED/Cuba: SOBERANA® 02 and SOBERANA® 02 ST: Two doses (0.5 mL each) 4 weeks apart.
Soberana Plus and Soberana Plus ST: Single dose (0.5 mL) as a booster vaccine 4 weeks after a primary schedule with SOBERANA® 02 or SOBERANA® 02 ST. |
CECMED/Cuba: if the benefits of the vaccination outweigh the potential risks. |
CECMED/Cuba: SOBERANA 02 and SOBERANA 02 ST: 2 years of age and older. Two doses (0.5 mL) 4 weeks apart. SOBERANA PLUS and SOBERANA PLUS as a booster dose 4 weeks after. |
CECMED/Cuba: SOBERANA 02 and SOBERANA 02 ST: Two doses (0.5 mL) 4 weeks apart. SOBERANA PLUS and SOBERANA PLUS as a booster dose 4 weeks after. |
CECMED/Cuba: SOBERANA 02 and SOBERANA 02 ST: Two doses (0.5 mL) 4 weeks apart. SOBERANA PLUS and SOBERANA PLUS as a booster dose 4 weeks after. |
CECMED/Cuba: SOBERANA® 02 and SOBERANA® 02 ST: Two doses (0.5 mL each) 4 weeks apart.
Soberana Plus and Soberana Plus ST: Single dose (0.5 mL) as a booster vaccine 4 weeks after a primary schedule with SOBERANA® 02 or SOBERANA® 02 ST. |
There is no available data on interchangeability. |
CECMED/Cuba: SOBERANA Plus and SOBERANA Plus ST may be used as a booster dose 4 weeks after a primary schedule with SOBERANA 02 or SOBERANA 02 ST. |
Gamaleya COVID-19 vaccine: Sputnik V; Gam-COVID-Vac; Spuntik Light (Authorized) [7],[8] |
Not recommended yet |
Not recommended yet |
Not recommended yet |
ANMAT/Argentina: Sputnik V: Two doses of different components (0,5ml each) 3 weeks apart. Sputnik Light: One dose (0.5 mL). |
ISP/Chile: if the benefits of the vaccination outweigh the potential risks. |
Not recommended yet |
Not recommended yet |
Not recommended yet |
ANMAT/Argentina: primary schedule with Sputnik V, followed by an additional (third) dose 4 months after with Sputnik V. |
ANMAT/Argentina: a heterologous scheme using Sputnik V component 1 followed by a second dose of any authorized mRNA-based or viral vector vaccine may be used. |
ANMAT/Argentina: A booster dose should be given at least 4 months after the primary scheme using an mRNA-based or viral vector vaccine. |
Janssen COVID-19 vaccine: Jcovden (EUL/WHO authorization) [9] |
Not recommended yet |
Not recommended yet |
Not recommended yet |
SAGE/WHO: One or two doses (0.5 mL each). WHO recommends providing two doses with an interval of 2 to 6 months. |
SAGE/WHO: One or two doses (0.5 mL each) 2-6 months apart. WHO recommends using the Janssen COVID-19 vaccine in pregnant women only if the benefits of vaccination outweigh the potential risks. |
Not recommended yet |
Not recommended yet |
Not recommended yet |
SAGE/WHO: Two doses (0.5 mL each) 1-3 months apart. |
SAGE/WHO: the homologous two-dose schedule is the standard practice. However, a heterologous scheme using a second dose of an mRNA vaccine may be more immunogenic and effective. |
SAGE/WHO: the need and timing of booster doses beyond the second dose are under assessment. |
Moderna COVID-19 vaccine: Spikevax (EUL/WHO authorization) [10] |
SAGE/WHO: for ages 6 months-5 years: Two doses (25 µg, 0.25 ml each) 4-8 weeks apart. |
SAGE/WHO: ages 6-11 years: Two doses (50 µg each) 4-8 weeks apart. |
SAGE/WHO: Two doses (100 µg, 0.5 ml each) 4 to 8 weeks apart. |
SAGE/WHO: Two doses (100 µg, 0.5 ml each) 4 to 8 weeks apart. |
SAGE/WHO: Two doses (100 µg, 0.5 mL each) 8 weeks apart. |
SAGE/WHO: Extended primary series with an additional (third) dose 1-3 months after the second dose, and two boosters (fourth and fifth doses) given 4-6 months after the previous dose. |
SAGE/WHO: Extended primary series with an additional (third) dose 1-3 months after the second dose, and two boosters (fourth and fifth doses) given 4-6 months after the previous dose. |
SAGE/WHO: Extended primary series with an additional (third) dose 1-3 months after the second dose, and two boosters (fourth and fifth doses) given 4-6 months after the previous dose. |
SAGE/WHO: Extended primary series with an additional (third) dose 1-3 months after the second dose, and two boosters (fourth and fifth doses) given 4-6 months after the previous dose. |
SAGE/WHO: Moderna COVID-19 vaccine combined with any other EUL COVID-19 vaccine is considered a complete primary series. |
SAGE/WHO: A booster dose should be given 4-6 months after the primary series* and a second booster after 4-6 months for specific population groups**.
WHO recommends Moderna COVID-19 vaccine as a heterologous booster. |
Novavax/ Serum Institute of India COVID-19 vaccine: Nuvaxovid; Covovax (EUL/WHO authorization) [11], [12] |
Not recommended yet |
Not recommended yet |
SAGE/WHO: Two doses (0.5 mL each) 3-4 weeks apart. |
SAGE/WHO: Two doses (0.5 mL each) 3-4 weeks apart. |
SAGE/WHO: Two doses (0.5 mL each) 3-4 weeks apart. |
Not recommended yet |
Not recommended yet |
SAGE/WHO: Extended primary series with an additional (third) dose 1-3 months after the second dose, and two boosters (fourth and fifth doses) given 4-6 months after the previous dose. |
SAGE/WHO: Extended primary series with an additional (third) dose 1-3 months after the second dose, and two boosters (fourth and fifth doses) given 4-6 months after the previous dose. |
SAGE/WHO: Novavax COVID-19 vaccine combined with any other EUL COVID-19 vaccine is considered a complete primary series. |
SAGE/WHO: A booster dose should be given 4-6 months after the primary series* and a second booster after 4-6 months for specific population groups**. |
Pfizer-BioNTech COVID-19 vaccine: Comirnaty (EUL/WHO authorization) [13] |
SAGE/WHO: Three doses (3 µg, 0.2 each). The first two doses administered 3 weeks apart, followed by a third dose 8 weeks after. |
SAGE/WHO: Two doses (10 µg, 0.2 mL each) 4 to 8 weeks apart. |
SAGE/WHO: Two doses (30 µg, 0.3 mL each) 4 to 8 weeks apart. |
SAGE/WHO: Two doses (30 µg, 0.3 mL each) 4 to 8 weeks apart. WHO recommends an interval of 8 weeks. |
SAGE/WHO: Two doses (30 µg, 0.3 mL each) 8 weeks apart. |
SAGE/WHO: Three doses (3 µg, 0.2 each), and two boosters (fourth and fifth doses) given 4-6 months after the previous dose. |
SAGE/WHO: Extended primary series with an additional (third) 10 µg dose 1-3 months after the second dose, and two boosters (fourth and fifth doses) given 4-6 months after the previous dose. |
SAGE/WHO: Extended primary series with an additional (third) 30 µg dose 1-3 months after the second dose, and two boosters (fourth and fifth doses) given 4-6 months after the previous dose. |
SAGE/WHO: Extended primary series with an additional (third) 30 µg dose 1-3 months after the second dose, and two boosters (fourth and fifth doses) given 4-6 months after the previous dose. |
SAGE/WHO: Comirnaty (Pfizer-BioNTech) combined with any other EUL COVID-19 vaccine is considered a complete primary series. |
SAGE/WHO: A booster dose should be given 4-6 months after the primary series* and a second booster after 4-6 months for specific population groups**.
WHO recommends Comirnaty vaccine as a heterologous booster. |
Sinopharm/BIBP COVID-19 vaccine: Covilo (EUL/WHO authorization) [7], [14] |
ANMAT/Argentina: 3 years of age and older. Two doses (0.5 mL each) 3 weeks apart. |
ANMAT/Argentina: Two doses (0.5 mL each) 3 weeks apart. |
ANMAT/Argentina: Two doses (0.5 mL each) 3 weeks apart. |
SAGE/WHO: Two doses (0.5mL each) 3 weeks apart. WHO recommends an interval of 3-4 weeks. |
SAGE/WHO: Two doses (0.5 mL each) 3 to 4 weeks apart. WHO recommends using the Sinopharm/BIBP COVID-19 vaccine in pregnant women only if the benefits of vaccination outweigh the potential risks. |
ANMAT/Argentina: 3 years of age and older. Two doses (0.5 mL) 3 weeks apart, followed by an additional (third) dose provided 4 weeks after. |
ANMAT/Argentina: Two doses (0.5 mL) 3 weeks apart, followed by an additional (third) dose provided 4 weeks after. |
ANMAT/Argentina: Two doses (0.5 mL) 3 weeks apart, followed by an additional (third) dose provided 4 weeks after. |
SAGE/WHO: Extended primary series with an additional (third) dose of 0.5 mL 1-3 months after the second dose, followed by a booster (fourth) dose provided 3-6 months after. |
SAGE/WHO: Sinopharm/BIBP COVID-19 vaccine combined with any other EUL COVID-19 vaccine is considered a complete primary series. |
SAGE/WHO: A booster dose should be given 4-6 months after the primary series* using any other EUL vaccine (preferably an mRNA-based or viral vector vaccine). |
Sinopharm/WIBP COVID-19 vaccine (Authorized) [15], [16] |
Not recommended yet |
Not recommended yet |
Not recommended yet |
NMPA/China: Two doses (0.5mL each) 3-4 weeks apart. |
NMPA/China: There is insufficient data on using the Sinopharm/WIBP COVID-19 vaccine during pregnancy. |
Not recommended yet |
Not recommended yet |
Not recommended yet |
NMPA/China: Two doses (0.5mL each) 3-4 weeks apart. |
NMPA/China: a heterologous booster schedule is recommended. |
NMPA/China: A booster dose should be given 6 months after the primary series using a protein subunit vaccine (Anhui Zhifei vaccine) or a viral vector-based one (CanSino vaccine). |
Sinovac COVID-19 vaccine: CoronaVac (EUL/WHO authorization) [8], [17] |
ISP/Chile: Two doses 2-4 weeks apart (dosage recommendation not yet available) |
ISP/Chile: Two doses (0.5 mL) 2-4 weeks apart. |
ISP/Chile: Two doses (0.5 mL) 2-4 weeks apart. |
SAGE/WHO: Two doses (0.5 mL each) 2-4 weeks apart. WHO recommends an interval of 4 weeks. |
SAGE/WHO: Two doses (0.5 mL each) 2-4 weeks apart. WHO recommends using the Sinovac COVID-19 vaccine in pregnant women only if the benefits of vaccination outweigh the potential risks. |
ISP/Chile: recommendation not yet available |
ISP/Chile: 3 years of age and older. Two doses (0.5 mL) 2-4 weeks apart and a booster (third) dose provided 2 months after. |
ISP/Chile: Two doses (0.5 mL) 2-4 weeks apart and a booster (third) dose provided 2 months after. |
SAGE/WHO: Extended primary series with an additional (third) dose of 0.5 mL 1-3 months after the second dose, followed by a booster (fourth) dose provided 3-6 months after. |
SAGE/WHO: CoronaVac (Sinovac) combined with any other EUL COVID-19 vaccine is considered a complete primary series. |
SAGE/WHO: A booster dose should be given 4-6 months after the primary series* using any other EUL vaccine (preferably an mRNA-based or viral vector vaccine). |
Valneva COVID-19 vaccine (Authorized) [18] |
Not recommended yet |
Not recommended yet |
Not recommended yet |
SAGE/WHO: Two doses (0.5 mL each) 4 weeks apart. |
SAGE/WHO: Two doses (0.5 mL each) 4 weeks apart. WHO recommends using the Valneva COVID-19 vaccine in pregnant women only if the benefits of vaccination outweigh the potential risks. |
Not recommended yet |
Not recommended yet |
Not recommended yet |
SAGE/WHO: Extended primary series with an additional (third) dose of 0.5 mL 1-3 months after the second dose, followed by a booster (fourth) dose provided 4-6 months after. |
SAGE/WHO: Valneva COVID-19 vaccine may be used as a booster dose following a primary series using Vaxzevria or Covishield. |
SAGE/WHO: A booster dose should be given 4-6 months after the primary series* using any other EUL vaccine. |
Vector Institute COVID-19 vaccine: EpiVacCorona (Authorized) [19] |
Not recommended yet |
Not recommended yet |
Not recommended yet |
Ministry of Health/Russian Federation: Two doses (0.5 mL) 3 weeks apart. |
Ministry of Health/Russian Federation: contraindicated in pregnant women. |
Not recommended yet |
Not recommended yet |
Not recommended yet |
Ministry of Health/Russian Federation: Two doses (0.5 mL) 3 weeks apart. |
There is no available data on interchangeability. |
There is no available data on booster doses. |